Milk thistle, benefits, side effects, dosage and interactions

Milk thistle is a flowering plant that has been used for centuries as a natural remedy in the treatment of liver and gallbladder diseases in most European countries. Milk thistle is also available as a food supplement. The milk thistle got its name from the milky sip which comes out of the leaves after breaking.

Milk thistle is a drought-resistant and cold-resistant plant that is no less caring; It is not difficult to increase. You can sow them before winter. Those who want to get strong plants faster, flowering and more seed formation, better root development usually grow it through seedlings.

Light fertile soils are most conducive to milk thistle and heavy and waterlogging are unsuitable. Milk thistle, benefits, side effects, dosage and interactions

Milk thistle grows rapidly: in mid-summer the plant reaches its maximum size, the baskets bloom in the central stems.

The more open the basket flowers in the shoots, the more they continue until very frost. The heads of the dried flowers will decorate any winter bouquet with bright baskets and milk thistle. Its seeds ripen unevenly from late August.

Since ancient times, milk thistle has been used to treat various, more severe, serious illnesses and very successfully. In the treatment of liver disease it is considered a powerful medicinal plant: cirrhosis, jaundice, alcohol, drugs, toxins, its wounds from radiation.

Milk thistle, benefits, side effects, dosage and interactions

Milk thistle is also used in the treatment of cholecystitis, inflammation of bile ducts and cholelithiasis, spleen, thyroid gland, blood, salt deposits, venous veins, edema, fever, obesity, sciatica and joint pain, hemorrhoids, allergic diseases.

The juice from its leaves is drunk for constipation, inflammation of the colon and gastric mucosa. Milk thistle seed flour lowers blood sugar levels, even cleanses the blood of large amounts of sludge and helps heal varicose veins.

Milk thistle is used not only for the sick but also for healthy people: the liver increases the body’s ability to clear toxins. Its most important property is that it has no contraindications and no side effects

Benefits and side effects of milk thistle

Milk thistle (Silibum liar) is a heart that has properties to improve liver health. The seeds contain silymarin, a group of compounds (including sildenabin, including sildianine and silicatein) that have antioxidant and anti-inflammatory effects and protect liver cells.

Some proponents claim that milk thistle can prevent certain types of cancer, including breast cancer and prostate cancer.

Milk thistle, benefits, side effects, dosage and interactions

Health facilities

Here’s a look at the science behind the potential health benefits of milk thistle:

1) Liver disease

Some preliminary studies have shown that cilantro can improve liver function by protecting the liver from toxins. However, studies on the effectiveness of milk thistle in the treatment of liver disease have yielded mixed results.

For example, according to a 2004 report published in the American Journal of Gastroenterology, most clinical evidence suggests that milk thistle does not improve liver function and does not reduce the risk of death in humans with alcoholic liver disease, hepatitis B, or hepatitis C.

Furthermore, some small studies have shown that milk thistle can improve liver function in people with cirrhosis, while other clinical trials have shown that milk thistle may be of little or no benefit to people with the disease.

2) Hepatitis C

Sometimes used by people with chronic hepatitis C (a viral infection that can invade and damage the liver).

Milk thistle, benefits, side effects, dosage and interactions

A survey of 1,145 participants in the NIH-funded HLT-C (hepatitis C antiviral long-term treatment aneurysm) test found that 23 percent of participants were using herbal supplements, the most common being milk thistle.

Examining participants’ medical and lifestyle histories, articipants reported that milk thistle was associated with mild to moderate liver disease and mild symptoms and some good quality of life, but no changes in liver virus activity or inflammation levels. Milk thistle, benefits, side effects, dosage and interactions

A 2012 survey published in JAMA examined the use of milk thistle (420 mg silamaria or 700 mg silamarin, taken three times daily) or placebo for 24 weeks. At the end of the treatment period, the researchers found that the milk thistle was no better than the pressure in a container to reduce blood levels, indicating liver damage.

Another study, published by Biomed Research International, found pre-Silimani studies for patients with chronic hepatitis C influenza. In their analysis, selenium could not be better than a placebo to improve laboratory quality (ALT and HCV RNA) or quality of life.

3) Diabetes

Several studies have shown that milk thistle can be beneficial for diabetics.

The most recent study on milk thistle and diabetes has been included in a study published in 2015 on pharmacodynamics. The study found that 40 patients with diabetes were treated with Silmarn or Placebo for 45 days.

At the end of the study, members of the silymarin group showed further improvement in antioxidant capacity and a greater reduction in inflammation than those given plasma.

According to the study’s authors, these results suggest that silymarin oxidative stress (a mechanism known to play a major role in the development of diabetic complications) may be beneficial to diabetics.

In addition, a number of small clinical trials conducted in recent years have found that milkweed can help control diabetes by controlling the progression of diabetes-related kidney damage.

4) Seasonal allergies

A small study published in Otolaryngology and Head and Neck Surgery in 2011 shows that silymarin can help prevent seasonal allergies. In a clinical trial of 94 people with seasonal allergies, researchers found a significant improvement in the severity of their symptoms (compared to a month of floodwear) treated with selenium for one month.

Possible side effects

Milk thistle can trigger a number of adverse side effects including tenderness, diarrhea, bloating and gas. It can cause headaches, fainting, joint pain, and sexual dysfunction. Allergic reactions such as trimming and difficulty breathing are difficult. Allergies can include allergies to daisies, artichokes, kiwis, common thistle, or milk thistle allergies.

In a study published in the International Journal of Food Microbiology, a high percentage of the milk thistle supplement samples tested were contaminated in the fungus. Whole seeds were the highest dose, then (no living fungi found in tea bags, liquid extracts, capsules or soft gels). Fungi produce toxic compounds known as mycotoxins.

Milk thistle can lower blood sugar levels, so it should be used with caution with diabetes and anyone taking medications or supplements that affect blood sugar levels.

Since there is a theoretical risk that milk thistle may have estrogen-like effects, milk thistle should be avoided in hormone sensitive conditions such as endometriosis, cervical fibritis, or breast cancer, baby or ovarian cancer. Milk thistle may reduce the effectiveness of oral contraceptives by inhibiting an enzyme called beta-glucuronidase. Milk thistle can change your body’s way of measuring and interacting with drugs in the liver.

Pregnant and breastfeeding women should avoid milk thistle. You can find tips on using supplements here, but keep in mind that the FDA does not regulate dietary supplements, so purity and source can vary greatly. If you are considering using milk thistle, be sure to talk to your healthcare provider first.

Milk Thistle: Dosage

Milk thistle fruit is included in a few blends of monotonous preparations and indication of indigestion / liver-bile disorder more commonly, but the drug is taken in the form of capsules, tablets, coated tablets and granular dried extract. Liquid preparations are also commercially available.

The average daily dose is 12-15 grams unless otherwise determined. Fruits calculated as milk thistle silabinin prepared from the average daily dose should be 200-400 mg silamarin.

Milk thistle, benefits, side effects, dosage and interactions

There are no guidelines for proper use of milk thistle. Milk thistle supplements are usually sold in capsule form but are also available as tablets, tea bags and oral tinctures. Doses range from 175 mg to one thousand mg. Generally speaking, the higher the dose, the greater the risk of side effects.

Combination remedies such as iberogast drops (used to treat dyspepsia) and barbaric tablets (made for diabetics) are considered effective with thistle doses of 10 mg and 210 mg of milk, respectively. High levels do not necessarily correspond to improved results. Milk thistle dietary supplements are sold in natural food stores, drug stores and specialty stores in herbal products. You can also buy milk thistle products online.


Milk thistle can lower your blood sugar, so it should be used with caution as it can trigger hypoglycemia (low blood sugar) in people with diabetes. Milk thistle may alter the way your body metabolizes certain drugs that trigger interactions with:

Milk thistle, benefits, side effects, dosage and interactions
  1. Biotin-like antibiotics (clarithromycin)
  2. Anticoagulants such as coumadin (warfarin)
  3. Nonsteroidal anti-inflammatory drugs (NSAIDs) such as Adil (ibuprofen), Celebrex (Celloxib) and Voltaren (Diclofenac)
  4. Statin drugs are similar to mevacar (lovastatin) and lescol (fluvastatin).
  5. Other interactions are possible. To avoid complications, always consult your doctor about any supplements or herbal remedies you have taken.

Other interactions are possible. To avoid complications, always consult your doctor about any supplements or herbal remedies you have taken.


This site uses Akismet to reduce spam. Learn how your comment data is processed.